Alobar Greywalker (alobar) wrote in longevity,
Alobar Greywalker

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Glutathione Snippets from Coconut Oil List

        Below are the many snippets I harvested from coconut oil list in response to my earlier post tonight, The Vital Key to Maximum Antioxidant Activity is Glutathione.


Deb & Laurie, the rate-limiting factor for glutathione production is cysteine, not in free form which is toxic, but delivered to the cells bonded to another amino acid, such as in the form of cystine or selenocysteine.
Undenatured whey is the best source of bonded cysteine. A method to tell wheys apart based on their glutathione precursors is at the bottom of this page:
 < >

Glutamine and glycine are also used in glutathione production but are not in short supply in the modern diet. The glutamine is more likely used to feed the bowel lining. Both glutamine and glycine also occur in the whey.

Selenium is also used but be aware that some highly touted sources like Brazil Nuts may contain no selenium at all unless they are grown in Brazil as opposed to Central America.

Undenatured whey is assimilated almost without digestion so it's a very good protein choice for the very young, the very old, and those with compromized digestion.

The blood work missed by Alobar has been done in many other humans and manmmals; the references are full of this kind of work and the merit of the undenatured whey approach has been established for about 10 years. For example, see the peer-reviewed cancer cures that used whey in the first few links here:

all good,


  You want naturally balanced proteins.  Your best sources would be fresh eggs or sprouted wheat.  Actually I would recommend a combination of both.

That way you not only get the specific things you are looking for, you also get all the added nutrition that nature put in there.  Eating natural foods does more to balance body chemistry than any man made, or processed, substance.
Nature understands nature, man does not.  Supplement sales people hate me, but the truth is the truth. 

Layne, you oughta like this then; the truth is that when the rate-limiting bonded cysteine is not in balance you don't have enough glutathione for optimal health.


No other food increases glutathione like undenatured whey, and naturally balanced proteins are not part of a glutathione discussion because they are too low in bonded cysteine to be useful glutathione promoters.
The truth is the truth on glutathione production. Data here:

all good,


Layne, I wrote that all people who lived to be 100 who had blood drawn had above normal glutathione levels.
I agree with whole foods but sometimes you need a purified one. If you don't want to believe in supplements you wouldn't be unique, but I think the data speaks for itself on elevating glutathione levels. 


So? were all those people who lived to be 100 taking whey protein isolate from now foods or somalife, or etc?  I don't think so.

In fact, those people living in the blue zone to over 100 years in Costa Rica sure don't look like they could afford to buy whey protein. So what is their secret for living active lives beyond 100? Can't be whey protein. Josephine 


The key to long life is keeping high glutathione levels.  It does not much matter if one does it thru diet, good genes, or supplements. Eat well for a year, then get your glutathione levels checked (see below info). If they are not high enough, take supplements, if you want to live a long life.

Testing for a Glutathione Deficiency?
There is no one test that demonstrates a glutathione deficiency with 100% accuracy. But there are some good tests that your doctor can order that will provide important clues if there is a deficiency, methylation dysfunction, or inability to detoxification.
Some tests available today are:
* Genova Diagnostics, Test: Plasma Sulfate & Plasma Cysteine; Test Type: Blood test.

Integrative Genomics, Test: Enhanced Basic Panel; Test type: Swab of the mouth.

These test kits are ordered by your doctor and via prescription only. For my family, the test results have been accurate and helped provide important clues for treatment protocols that have significantly helped my son.



Josephine, let me explain: people over 100 occur naturally as one in three thousand or so, just as a guess for argument; we'll revise that if we have to. You have the same 1:3000 chance of hitting 100 years old without the undenatured whey, as some of the tribes of primitive people you mentioned who also do not use whey powder.
From WIKI: "Much rarer, a supercentenarian is a person who has lived to the age of 110 or more, something only achieved by about one in a thousand centenarians. Even rarer yet is a person who has lived to 115 years old; only 1 in 100,000 centenarians make it to this age."

While some people, like you perhaps, HOPE to hit 100, others KNOW they have a better chance of BEING one of those people. Since NOBODY in the lower glutathione group sees their 100th birthday, we'll increase glutathione thank-you.

Undenatured whey is an anti-aging tool anyway, well supported by facts and use. A read of titles such as glutathione in aging, in brain function and in cancer treatment would be an eye-opener; I have many of those titles in my glutathione references:

The anti-aging doctors say in order to age well, don't get sick. Glutathione helps to prevent one from getting sick, as it forms the seat of immune response. I take the whey because ensuring high glutathione is more proactive for health and age management than simply holding out the hope that I would be in the 1:3000 lucky ones.


Do you have any evidence that "NOBODY in the lower glutathione group sees their 100th birthday"? 


  Emma, from a Google on centenarians glutathione: "...centenarians exhibit a high activity of glutathione reductase in red blood cells. In this study, those centenarians having the best cognitive and physical functional capacity tended to have the highest activity of this enzyme.[6]"

...among several other cites from the WIKI given as listing #4.

Good enough for me, but the search turned up lot more on the subject.


  "in comparison with young healthy female adults the centenarians had significantly higher red blood cell glutathione reductase and catalase activities and higher, although insignificantly, serum vitamin E level."
"The range of Glutathione Reductase activity was shifted toward higher values in the centenarian group than in the younger (age 60-79)group and those centenarians having the best functional capacity tended to have the highest GR activity"


If you want to extend this line of logic even further and make the most of the glutathione you have AND that you supplement with, use R-ALA. This recycles / reactivates glutathione after it becomes inactive through use...which is amasing to me. Plus,it recycles,Vit c.COQ10 and many others. If you get it in powder form and not tablet,its $100 for 2 years. But you will need some acurate scales to measure it.

Its really helped my liver which has always been sluggish.

Its also been used in Cancer treatment along with Low Dose Naltrexone. Amasing stuff !

[Note by Alobar:  Looks like $100 is more like a 3 month supply to me.  See
R-Dihydro-Lipoic Acid: The Optimal Form of Lipoic Acid   ]

I'm getting whey info "overload".....I have a few cans of whey leftover from the days before I switched to my fav brand, Jay Robb--and I'm looking at the labels and getting confused at the terms......can someone please help.....???
Ion Exchanged,
(they all say whey protein isolate)
and NONE of them says cold-pressed or heat pressed, how to I know....???
Blessings, Margaret 


Margaret, compare the labels with the method I laid out at the bottom of my whey page:
You'll need the company to divulge the proteins or the (cold, low, carefully-controlled) temperature of the extraction method. If they don't, they probably have not put undenatured whey in the jar.

all good,


Make your own with Raw milk.  It is super easy.  If you want to know just ask. And you get cream cheese when you make whey from raw milk. 


Raw whey -- 2 servings of glutathione precursors is about 10 gallons daily, so it really has to be dried to concentrate it enough to be a good health food.



The whey that is patented as a drug with legal health claims, Immunocal, is an isolate.

Depends on what was isolated and how well, I suppose, and whether they chose the right whey for the test application. Not everyone is using raw whey for glutathione increase; cheaper boiled product is mainly used in body building.



Immunocal is listed in Dr. Mercola's copy of the Physician's Desk Reference. It is a chemotherapeutic and an anti-cachexic with glutathione mention in the PDR.

Obviously, whey isolates ARE assimilated. I've seen other examples on Mercola's site that make me think he doesn't write his own copy.



Does whey contain casein? 


Casein is removed from milk, leaving whey. The whey should contain no more than a trace.



That Mercola article is misleading at best as not all isolates are processed in the same manner.
For a more accurate description on the differences between whey concentrate, ion exchange isolate, and CFM isolate, see:
(which I posted to my LJ here:

  A lot has been said about Glutathione,so i thought Id post a link about how it can be recycled/reactivated along with  vitamins C and E, CoQ10.

This is done with R-ALA... NOT ... ALA,you need to get the stabilised "R" version.

R-ALA supplier from the only manufacturer in the USA who makes it in pure,no fillers,powder form.

Powder from this supplier,is absorbed like an intravenious solution,which enables it to work properly. Tablet form doesn't allow the absorbtion like powder does. Quick absorbtion is what allows R-ALA to do its thing.
A Dr Berkson has cured people with Pancreatic terminal cancer using R-ALA along with Low Dose Naltrexone..LDN.

Again, that's another "supplement" to add to the $100.00  list.........why is it ONLY THIS SUPPLEMENT WILL WORK......??  Do you  have any affiliation with this company or product.....?  Why is it only this supplement----if I did an informal poll  of average of all the people who have reached 100 yrs. old and are  healthy, I'm betting none of them takes it--okay, maybe one or two---I  know couple of 100 yrs. old people and they don't use anything at  all........why do I need this.....?

Blessings, Margaret 


For me, it is an easy question to answer.  Because some people make it to 100 without supplements does not mean most people can do it.  The quality of foods has gone down over the past 50-100 years.  Veggies are picked long before they are ripe and shipped long distances. Crops are fertilized with n-p-k fertilizer instead of cow manure, so veggies are low in trace minerals.  Air quality is far worse now than back 100 years ago. There are medical wastes in most municipal water supplies.  People in civilized nations do not work nearly as hard as peasants in a third world country.  Not using one's body a lot is not conducive to living long.

Even before all the foibles of modern life, very very few people made to 100.  Now, I suspect it will be less and less.  So I am willing to take supplements to better my chances of living a long healthy life. Currently I spend as much on supplements as I do on food.  I eat out in a restaurant once or twice a year.  I never eat fast food or junk foods.

A philosopher I used to know had a saying: I'll live forever or die trying.  So I spend hours every day doing research.  I spend my discretionary money on my health.  And do what I can.


People with this Factor Live Past 100

Dear Health Conscious Reader,

Cutting-edge research is revealing the power of a “master antioxidant” – a tripeptide molecule called glutathione (GSH).

People with the highest levels of GSH are the ones who routinely live past 100. Plus, it may prevent a host of chronic diseases like arthritis, high blood pressure, heart disease, cancer and diabetes – just to name a few.

Best of all, boosting your levels of GSH is easy. Today, I’ll give you an effective strategy that may add decades to your life. I’ll tell you exactly how to get the most powerful forms of GSH and how much to take.

When scientists at the University of Louisville gave mosquitoes a GSH booster, their levels went up by 50 to 100 percent. And, their life spans increased by a remarkable 30 to 38 percent.1

Doctors at the Montreal General Hospital Research Institute in Canada then repeated the experiment with mice. They were able to duplicate the results – boosting levels of GSH and increasing life spans.2

Their success prompted others to investigate the effects of GSH in humans. Odense University in Denmark compared levels of GSH in centenarians (age 100 to 105) and people age 60 to 79 and found that GSH was higher in the centenarians. And among the centenarian group, those who were the most active had the very highest levels.3

In the same way that high levels of GSH increase life spans, low levels of GSH show a direct link to chronic degenerative diseases. Here’s just a partial list:

    * Heart Disease
    * Cataracts
    * Arthritis
    * Renal Failure
    * High Blood Pressure
    * Leukemia
    * Diabetes
    * Hearing Loss
    * Cancer
    * Obstructive Lung Disease (COPD)
    * Macular Degeneration

And high levels of GSH are associated with fewer illnesses. A University of Michigan study found that those with higher GSH levels reported a greater sense of well being along with lower blood pressure, lower cholesterol and reduced body fat.4

The most natural way to get more GSH is eating foods high in glutathione. These include horseradish, broccoli, cauliflower, cabbage, kale and Brussels sprouts.

These nutritional supplements will also boost your GSH:
    * Alpha Lipoic Acid (ALA)
    * Melatonin
    * Bilberry
    * Grape Seed Extract
    * Turmeric

There are also two reliable GSH precursors – substances that stimulate the production of GSH. These are whey protein5, commonly found in protein powders and N-acetyl cysteine6 (in a dose of 1,800 mg to 2,400 mg a day) – both are available at your local nutrition and/or health food stores.

Finally, you can take GSH supplements (1 to 2 grams per day). The latest reports show that up to 80 percent of most GSH supplements are absorbed and used by your body.

For best results, I recommend using a combination of all four ways to boost GSH.

To Your Good Health, Bookmark and Share

Al Sears, MD

   1. Richie JP, et al. Correction of a glutathione deficiency in the aging mosquito increases its longevity. Proc Soc Exp Biol Med. 1987 Jan;184(1):113-7.
   2. Buonous G, et al. Immunoenhancing property of dietary whey protein in mice: Role of glutathione. Clin Invest Med. 1989b;12:154-161.
   3. Andersen HR, Lower Activity of Superoxide Dismutase and High Activity of Glutathione Reductase in Erythrocytes from Centenarians, Age and Aging, 1998;27:643-648.
   4. Julius M. Glutathione and morbidity in a community-based sample of elderly. Journal of Clinical Epidemiology. 1994;47(9):1021-1026.
   5. Bounous G, et al. The influence of dietary why protein on tissue glutathione and the diseases of aging. Clin Invest Med. 1989a Dec;12(6):343-9.
   6. Schaller M. Oxidant-Antioxidant Balance in Granulocytes During ARDS-Effect of N-Acetyl cysteine, Chest, Jan 1996;109(1):163-166.

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